Umbilical cord blood therapy for cerebral palsy
Overview:
This randomised, placebo-controlled, double-blind clinical trial
used donated (allogeneic) cord blood in conjunction with the hormone
erythropoietin in children with cerebral palsy (CP). The study
results showed significant improvements in the motor and cognitive
function of these children. The improvements with cord blood were
more favourable when the donor was a closer match to the patient,
suggesting great potential for autologous (child’s own) cord blood
transfusion in patients with CP.
Location: South Korea
Trial design: Safety and efficacy
Status: Completed
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Autologous umbilical cord blood reinfusion in children with cerebral palsy
Overview:
In a larger clinical trial at Duke University researchers are
evaluating the effectiveness of autologous (child’s own) cord blood
infusion in the treatment of children with CP. This randomised,
controlled trial aims to recruit 120 children with CP over a 2 year
period. Participants will be given their own cord blood or a placebo
to determine the effects on their neurodevelopmental function and
quality of life. The study is estimated to be completed in January
2016.
Location: North Carolina, USA
Trial design: Efficacy study
Status: Active - not recruiting
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Safety and effectiveness of cord blood in cerebral palsy in children
Overview:
This clinical trial is assessing the safety and effectiveness of an
infusion of autologous (child’s own) cord blood in children who have
motor disability due to cerebral palsy. The researchers are
currently recruiting (up to 40) children between the ages of 1 and
12 years with cerebral palsy with an estimated completion date in
July 2015.
Location: Georgia, USA
Trial design: Safety and efficacy
Status: Open - currently recruiting
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